Tuesday, September 18, 2018


     The prostate cancer usually grows over time and in the beginning usually stays within the prostate gland, where it may not cause serious harm. Also, some types of prostate cancer grow slowly and may need minimal or no treatment, other types are aggressive and can spread quickly. Prostate is a small gland located underneath the bladder in men and is part of the reproductive system. Some men develop prostate cancer, usually later in life. If cancer develops on your prostate gland, it will likely grow slowly. However, the cancer cells may be more aggressive, grow quickly, and spread to other areas of your body. The earlier your doctor finds and treats the tumor, the higher the chances are of finding curative treatment.
According to the Urology Care Foundation, prostate cancer is the second most common cause of all cancer-related deaths among American men. About 1 in 7 men will be diagnosed with the disease in their lifetime. Approximately 1 in 39 men will die from it. Most of these deaths occur among older men.
      Also, multiple factors may be involved, including genetics and exposure to environmental toxins, like certain chemicals or radiation.
Ultimately, mutations in your DNA, or genetic material, lead to the growth of cancerous cells. These mutations cause cells in your prostate to start growing uncontrollably and abnormally. Abnormal or cancerous cells continue to grow and divide until a tumor develops. If you have an aggressive type of prostate cancer, the cells may metastasize, or leave the original tumor site and spread to other parts of your body.

     There are usually no symptoms during the early stages of prostate cancer. Also, if symptoms do appear, they usually involve one or more of the following:
1.  Frequent urges to urinate, including at night.
2.  Difficulty commencing and maintaining urination
blood in the urine.
3.  Painful urination and less commonly.
4.  Ejaculation difficulty achieving or maintaining an erection will be difficult.

     Advanced prostate cancer can involve the following symptoms:
 Bone pain, often in the spine, femur, pelvis, or rib
bone fractures.

If the cancer spreads to the spine and compresses the spinal cord, there may be:
1.  Leg weakness
2.  Urinary incontinence
3.  Fecal incontinence.

      Factors that affect your chances of developing prostate cancer, including your:
1.  Family history
2.  Age
3.  Race
4.  Geographical location
5.  Diet

Family history
The mutations that lead to prostate cancer are inherited. If you have a family history of prostate cancer, you're at increased risk of developing the disease yourself, because you may have inherited damaged DNA.

     Research shows, approximately 5-10 percent of prostate cancer cases are caused by inherited mutations. It's been linked to inherited mutations in several different genes, including:
RNASEL, formerly known as HPCI
BRCA1 and BRCA2, which have also been linked to breast and ovarian cancer in women MSH2, MLH1, and other DNA mismatch repair genes HOXB13.

One of the biggest risk factors for prostate cancer is age. This disease rarely affects young men. The Prostate Cancer Foundation reports that only 1 in 10,000 men under the age of 40  develop it. That number jumps to 1 in 38 for men between the ages of 40 and 59. It leaps to 1 in 14 men between the ages of 60 and 69. The majority of cases are diagnosed in men over 65.

Race and ethnicity
Although the reasons aren’t fully understood, race and ethnicity are risk factors for prostate cancer. According to the American Cancer Society , in the United States, Asian- American and Latino men have the lowest incidences of prostate cancer. In contrast, African-American men are more likely to develop the disease than men of other races and ethnicities. They are also more likely to be diagnosed at a later stage and have a poor outcome. They are twice as likely to die from prostate cancer as white men.

A diet that's rich in red meat and high-fat dairy products may also be a risk factor for prostate cancer. A study published in 2010 looked at 101 cases of prostate cancer and found a correlation between a diet high in meat and high-fat dairy products and prostate cancer, but stressed the need for additional studies.
Also, from a recent study looked at the diet of 525 men newly diagnosed with prostate cancer and found an association between high- fat milk consumption and the progression of the cancer. This study suggests that high-fat milk consumption may also play a role in the development of prostate cancer.
Men who eat diets high in meat and high-fat dairy products also seem to eat fewer fruits and vegetables.

Geographical location
Environment can also impact your risk of developing prostate cancer. While Asian men living in America have a lower incidence of the disease than those of other races, Asian men living in Asia are even less likely to develop it. According to the American Cancer Society, prostate cancer is more common in North America, the Caribbean, northwestern Europe, and Australia than it is in Asia, Africa, Central America, and South America. Environmental and cultural factors may play a role.
The Prostate Cancer Foundation notes that in the United States, men living north of 40 degrees latitude are at a higher risk of dying from prostate cancer than those living farther south. This may be explained by a reduction in the levels of sunlight, and therefore vitamin D, which men in northern climates receive. There's some evidence that vitamin D deficiency may increase risk for prostate cancer.
Aggressive prostate cancers may be slightly different than slower-growing types of the disease. Certain risk factors have been linked to the development of more aggressive types of the condition. For example, your risk of developing aggressive prostate cancer may be higher if you:
and obese
have a sedentary lifestyle
consume high levels of calcium.

     Certain things that were once considered risk factors for prostate cancer are now believed to have no connection to the disease.
     Your sexual activity doesn’t appear to have any impact on your chances of developing prostate cancer.
Having a vasectomy doesn't appear to increase your risk.
There's no known link between alcohol consumption and prostate cancer.
Although some cases of prostate cancer are aggressive, most are not.

      Most men diagnosed with this disease can expect a good outlook and many years of life ahead of them. The earlier your cancer is diagnosed, the better your outlook. Diagnosing and treating prostate cancer early can improve your chance of finding curative treatment. Even men who are diagnosed in later stages can benefit greatly from treatment.

These benefits include; 
Reducing or eliminating symptoms.
Slowing further growth of the cancer.
Prolonging life by many years.

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